Lyons Drug Store has been a part of downtown Lonoke since Mr. and Mrs. Lyons opened the original location, on the corner of Front and Center street by the town’s only stop light! Mr. Lyons passed away in 1964. Although she was not a pharmacist, Mrs. Lyons retained ownership and grew the business for years. Rick Pennington, after three decades working with the pharmacy, went on to purchase Lyons Drug Store on January 1, 2005. The Lyons Drug Store Scholarship was introduced the same year and has been awarded annually since.

In May of 2007, Lyons Drug Store moved to our current location on 115 West Front St, in the former McCrary Clothing Store building. The space gave us room to expand our gift shop while still being in the same block as the original pharmacy.

We’re thrilled to bring you the best gifts from the biggest brands – and even more proud to offer local products and personal service. Lyons Drug Store and Gift Shop offers everything from cards to home decor – you’re sure to find the perfect gift for everyone on your list!